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Life Sciences

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Published yearly: 

4 Issues

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ISSN: 2320-964X (Online) 

ISSN: 2320-7817  (Print)

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Editor-in-Chief

Dr. Santosh Pawar 


INDEXED IN

ORIGINAL ARTICLE

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Int. Journal of Life Sciences, 2016; 4(3):379- 384   |    Available online, October 8, 2016

Invitro studies on the primitive pharmacological activities of Adhatoda vasica

 

 

Suganthi Nagarasan1 and Boominathan  M2*

1Department of Biotechnology, Marudhupandiyar College, Vallam, Thanjavur, Tamilnadu, India.

2Department of Botony, Government Arts College (Men), Kumbakonam- 612 002, Tamilnadu, India.

*Corresponding author Email: boomi_26@yahoo.com

 

 

Received: 12.08.2016   |   Accepted: 21.09.2016   |   Published : 08.10.2016 

Adhatoda vasica is an indigenous herb belonging to family Acanthaceae has been used in the Indian system of medicine. It was spread all over the India and in some other Asian countries. It contains some phytochemicals such as alkaloids, tannins, flavonoids, terpenes, and glycosides. Alkaloids like vasicine, vasicinone, and vasicinol from leaves and roots, flavonoids like apigenin, kaempferol, astragalin, etc, and triterpenes like daucosterol from flowers have been isolated for the study of pharmacological activities such as Antioxidant, antibacterial, antifungal and anti-inflammatory activities. In the present study we clearly investigate the in vitro activity of Adhatoda vasica against bacteria, fungi and oxidative stress. Our research reveals that the aqueous, ethanol and chloroform extracts shows maximum inhibitory effect against various bacteria and fungi. In addition to that we proved that these extracts also have antioxidant activity.

 

Key words: Antioxidant, Antibacterial, Antifungal, DPPH.

 

 

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Editor: Dr. Arvind Chavhan

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Cite this article as:

Suganthi Nagarasan and Boominathan M(2016) Invitro studies on the primitive pharmacological activities of Adhatoda vasica, International J. of Life Sciences, 4 (3): 379-384.

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Acknowledgement:

We sincerely thank to Mr. B. Purushothaman, Research Head, TANBIO R and D solution,  during various analysis in his lab and Mr. R. Prasanna Srinivasan lab assistant TANBIO R and D solution

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Conflicts of interest: The authors stated that no conflicts of interest.

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Copyright: © 2016 | Author(s), This is an open access article under the terms of the Creative Commons Attribution-Non-Commercial - No Derivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Balakrishnan P, Musafar Gani TA, Subramanium S, Shanmugam K (2015) A perspective on bioactive compounds from Solanum trilobatum J. chemical and pharmaceutical research, 78: 507- 12.


Kumar G, Karthik L, Rao KVB (2013) Phytochemical composit ion and in vitro antioxidant activity of aqueous extract of Aerva lanata (L.) Juss. ex Schult. Stem (Amaranthaceae). Asian Pacific J.Tropical Medicine, 6: 180-187.


Meignanalakshmi S, Vinoth Kumar S, Deepika J, Farida Begum I (2013) Evaluation of antibacterial activity of methanol extract of leaves of Adhatoda vasica on mastitis pathogens, Hygeia.J.D.Med.5:1-4.


Palombo EA, Semple SJ (2001) Antibacterial activity of traditional medicinal plants. J. Ethnopharmacology 77: 151-157.


Rathnasamy S, Auxilia R, Balakrishnan B (2014) Comparative Studies on Isolation and Characterization of Allinase from Garlic and Onion using PEGylation- a Novel Method. Asian J. of Chemistry, 26 : 3733-5.


Rashmi Pa, Linu Mathew (2012) Antimicrobial activity of leaf extracts of Justicia adhatoda L. in comparison with vasicine, Asian Pacific J.Tropical Biomedicine, 1556-60.


Samy RP, Ignacimuthu S (2000)  Antibacterial activity of some folklore medicinal plants used by tribals in Western Ghats in India, J. Ethnopharmacology 69:63-71. 


Stepanovic S, Antic N, Dakic  I, Svabic- vlahovic M (2003) In vitro antimicrobial activity of propilis and antimicrobial drugs, Microbiology Research. 158: 353-357.


Suganthi Nagarasan,M. Boominathan (2016) Perspective pharmacological activities of Leucas aspera: an indigenous plant species. Indo Am. J. of Phar. Res. Accepted article


Sundaramoorthy M, Prabaharan C, Purusothaman B, Saravanan TS (2014) Antibacterial and Wound Healing Effects of Semi-Purified Heart Proteins from Certain Selective Slaughter House Animals. Indo Am. J. of Phar. Res. 4 :1021-8.

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    INTERNATIONAL JOURNAL OF

    LIFE SCIENCES

    Print ISSN : 2320-7817 

    Online ISSN:2320-964X

    UGC Approved Journal No. 48951


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