Image description

Published yearly: 

4 Issues

______________________

ISSN: 2320-964X (Online) 

ISSN: 2320-7817  (Print)

______________________

Editor-in-Chief

Dr. Santosh Pawar 


INDEXED IN

RESEARCH ARTICLE

_______________________________________________________________________________________

Int. Journal of Life Sciences, 2018; 6(2): 427-433       |                 Available online, April 25, 2018

Evaluation of phytochemicals, antioxidants and anti-inflammatory activity of fresh leaf and flower extracts of Tagetes erecta L. grown in Kalaburagi


Rathod Manjula A1* and Mathad Pratima2

 

1Manjula Rathod, Ph. D. Scholar. Dept. Of P.G. Studies and Research in Botany, Gulbarga University, Kalaburagi-585106. Karnataka, India. 

2Dr. Pratima Mathad,Professor Dept. Of P. G. Studies and Research in Botany, Gulbarga University,  Kalaburagi-585106. Karnataka, India

*Corresponding author Email: manjularthod@gmail.com | unipm@rediffmail.com

Received : 16.01.2018   |   Revised :  09.03.2018   |  Accepted : 29.03.2018    |    Published : 24.04.2018

Tagetes erecta L.  (Asteraceae) is used to treat epileptic fits (Ayurveda), fever, wounds and   microbial infections of livestock’s in folklore medicine of Kalaburagi district.  As little work has been carried out on fresh material so present study aims to evaluate aqueous extracts of fresh leaf and flower for phytochemicals, antioxidants and anti-inflammatory activities. The results revealed that the leaf extract was rich in primary as well as secondary metabolites as compared to flower extract. The physicochemical analysis such as moisture, crude fat, crude fibre content and total ash values found higher in leaf extract than flower extract.  The DPPH and Nitric oxide radical scavenging activity found higher in flower extract than the leaf extract when compared to standards. Whereas the Hydrogen peroxide and Reducing power assay of leaf extract showed higher activity than flower extract at different concentrations. Anti-inflammatory activity showed that the HRBC membrane stabilization activity of leaf extract was found higher than flower extract and albumin denaturation activity of flower extract was found higher than leaf extract. From the study it is evident that the fresh leaf and flower extracts of Tagetes erecta are effective source of naturally and pharmacologically active compounds which can be used in herbal remedies.

 

Key words: Phytochemicals, Free radicals, proximate analysis, anti-inflammatory Tagetes erecta, leaf, flowers, Kalaburagi.


_________________________________________________________________________

Editor: Dr.Arvind Chavhan

___________________________________________________________________________________ 

Cite this article as:

athod Manjula A and Mathad Pratima (2018) Evaluation of phytochemicals, antioxidants and anti-inflammatory activity of fresh leaf and flower extracts of Tagetes erecta L. grown in Kalaburagi., Int. J. of. Life Sciences, Volume 6(2): 427-433. 

____________________________________________________________________________

Acknowledgement

Author likes to thanks UGC, Rajiv Gandhi National Fellowship for SC students  (JRF) for providing financial support to the study. 

____________________________________________________________________________


Conflicts of interest: The authors stated that no conflicts of interest.

____________________________________________________________________________

 

Copyright: © 2018 | Author(s), This is an open access article under the terms of the Creative Commons Attribution-Non-Commercial - No Derives License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

_________________________________________________________________________

 

Arefin Sayema, Md. Islam Towhidul & Hossain. Md. Tanvir.  (2015) Proximate analysis, Phytochemical screening and antioxidant activity of Tagetes erecta flower growing in coastal area of Bangladesh. Journal of  Global  Biosciences,  4  no 4 pp.2060-2066.


Dharsana JN and DR Molly Mathew SR  (2015) Anti-inflammatory activity of Morinda umbellata by membrane stabilization method. International Journal of Pharma and Bio Sci,  6 (1), P 349–353.


Ferreira Isabel CFR, Baptista Paula, Vilas-Boas  Miguel  (2011) Free-radical scavenging capacity and reducing power of wild  edible mushrooms from northeast Portugal Individual cap and stipe activity,  Elsevier Food Chemistry. 100, 1511–1516.


Bjelakovic  G, Nikolova D, Gluud  C (2013) Meta-regression analyses, meta-analyses, and trial sequential analyses of the effects of supplementation with beta-carotene, vitamin A, and vitamin E singly or in different combinations on all-cause mortality: do we have evidence for lack of harm?.


Gayathri S Sree and Daniel Rachel Regi (2015) Nutritional Potentiality and Elemental Analysis of Leaves of selected medicinal plants. Journal of Scientific Research, 4 (4).


  Gopi G, Elumalai A and Jayasri P  (2012) A concise review on Tagetes erecta. International Journal of Phytopharmacy Research,  1 (30) 16-19.


Hussain A Zakhir and Kumarsen  (2012) Antimicrobial activity and heavy  metal analysis of Ipomoea  obscura. L, Journal of Microbiology and Biotechnology Research, 4  (5), 18-23.


Mahadevan V, Vadivel V and Brindha P  (2016) In vitro antioxidant and anti-inflammatory activities of aqueous extract of an Ayurvedic formulation Dasamula and its herbal ingredients: A comparative study.  International Journal of Green Pharmacy,  10  (4)  S 211.


Mathad Pratima, Sikandari Sumayya, Honnalli Jyothi and Patil Anil Kumar  (2016) Phytochemical studies of two selected Unani medicinal plants of Kalaburagi region, Karnataka, India. International Journal of Pharmaceutical Sciences and Research, 7 (6), 2597-2605.


Mathad Pratima, Sikandari Sumayya, Honnalli Jyothi and Patil Anil Kumar.  (2016) Phytochemical studies of two selected Unani medicinal plants of Kalaburagi region, Karnataka, India. International Journal of Pharmaceutical Sciences and Research, 7 (6), 2597-2605.


Natasha Kamat, Prajakta Barve, Yogita Sawant, Lalitha Shree SJ  (2016) Phytochemical analysis of leaf extracts of Annona muricata. Proceedings of the National Seminar on ‘Herbal Technology & Ethanobotany’, p46-50.

Jayanthi P and Lalitha P (2011) Reducing power of the solvent extracts of Eichhornia crassipes   (Mart.) Solms,  Int J Pharm Pharm Sci, 3,  (3), 126128.


Prabha Saravana P, Gopalakrishnan VK (2015) In vitro free radical scavenging activity of Ipomoea obscura  (L.) KER – GAWL. Leaf,  Indo American Journal of Pharm Research, 5 (03).


Sadashivam S and Manickam (1991) Biochemical methods, New Age International  (P) Limited , p 12-13.


Shetty Lokesh J, Farouk Sakr M, Kais Al-Obaidy, Patel Mohammed J, Hidayatullah Share f  (2015) A brief review on medicinal plant Tagetes erecta Linn. Journal of Applied Pharmaceutical Science, Nov 5 (suppl_3), S91-S95.

Summne and  Judith  (2000). The Natural History of Medicinal Plants, Timber Press, p16.


Sundar Shalini, Sudevan Susmitha, Paramasivam Ranganayaki and Vijayaraghavan R  (2015)  Evaluation of In-vitro Anti-inflammatory Activity of Aqueous Extract of Andrographis paniculata. Global Journal of Pharmacology,  9  (4): 289-295,


Theng KB, Korpenwar AN (2015) Quantitative Estimation of Some Phytochemical and Determination of  metallic elements from  Pueraria tuberosa  (Roxb. Ex Willd.) DC. Tuber. International Journal of  Science and Research  (IJSR) ,  4  (2).


Thimmiah SR (1999) Standard methods of biochemical analysis,  (1999) and 2006. p 421-426.


Valyova Miglena, Stoyanov Stanimir, Markovska Yuliana, Ganeva Yordanka.  (2012) Evaluation of in vitro antioxidant activity and free radical scavenging potential of variety of Tagetes erecta L. flowers growing in Bulgaria. International Journal of Applied Research in Natural Products, 5  (2), pp. 19-25. 

        

Vishnuvathan VJ,  Lakshmi KS and Srividya AR  (2017) Study of antioxidant activity of Formononetin by  in vitro method. Int J Pharm Sci.  9 (2), 273-278..

 

IJLSCI EVENTS

ADVERTISEMENT

 
















    INTERNATIONAL JOURNAL OF

    LIFE SCIENCES

    Origin & Evolution

    Print ISSN : 2320-7817 

    Online ISSN:2320-964X

    UGC Approved Journal No. 48951


    EDITORIAL OFFICE

    46, Guruwandan, Jawahar Nagar, 

    VMV Road, Amravati- 444604

    Maharashtra, India.

    Tel  + 91- 9970559438  |   9420775527  

    Email: editor@ijlsci.in | editorijlsci@gmail.com