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Published yearly: 

4 Issues

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ISSN: 2320-964X (Online) 

ISSN: 2320-7817  (Print)

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Editor-in-Chief

Dr. Santosh Pawar 


INDEXED IN

RESEARCH ARTICLE

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Int. Journal of Life Sciences, 2018; 6(2): 441-445       |                 Available online, April 25, 2018

Bacteriophage therapy for treating multiple-drug resistant urinary tract pathogen, Escherichia coli


Rima Das1, Anusha Balasingh2* and Anupama R3

 

1 Post Graduate Scholar, Department of Microbiology, Ethiraj College for Women, Chennai - 600008, Tamil Nadu, India

2 Assistant Professor, Department of Microbiology, Ethiraj College for Women, Chennai - 600008, Tamil Nadu, India

3 Post Graduate Scholar, Department of Microbiology, Ethiraj College for Women, Chennai - 600008, Tamil Nadu, India

*Corresponding Author: Anusha Balasingh, Assistant Professor, Department of Microbiology, Ethiraj College for Women, Chennai- 600008, Tamil Nadu, India 

Received : 19.02.2018       |    Accepted : 12.04.2018        |        Published : 25.04.2018

The aim of the study is to prove the efficacy of phage therapy for treating multi drug Resistant (MDR) Escherichia coli isolate from urine sample of UTI patient. The clinical isolates of E.coli was obtained from 5 out of 10 urine samples of Urinary Tract Infection (UTI) patients using Hicrome UTI agar. The isolate was checked for their resistance, by using antibiotic susceptibility test. The multidrug resistant (MDR) isolate was further subjected to phage susceptibility test using lambda phage and phages isolated from sewage. The lambda phage and phages isolated from sewage was found highly lytic to MDR E.coli. Phage therapy can be used for treating MDR E. coli and can even compensate the progressively failing antibiotics.

 

Keywords: Urinary Tract Infection, Multidrug Resistant E.coli, Bacteriophage, Phage therapy

 

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Editor: Dr.Arvind Chavhan

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Cite this article as:

Das, Rima, Balasingh Anusha and Anupama R (2018) Bacteriophage therapy for treating multiple-drug resistant urinary tract pathogen, Escherichia coli., Int. J. of. Life Sciences, Volume 6(2): 441-445.

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Acknowledgement:

The authors would like to thank Charutar Vidya Mandal (CVM), Vallabh Vidyanagar for providing platform and necessary support to carry out this research. 

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Conflicts of interest: The authors stated that no conflicts of interest.

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Copyright: © 2018 | Author(s), This is an open access article under the terms of the Creative Commons Attribution-Non-Commercial - No Derives License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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