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Published yearly: 

4 Issues


ISSN: 2320-964X (Online) 

ISSN: 2320-7817  (Print)



Dr. Santosh Pawar 




Int. Journal of Life Sciences, 2018; 6(4): 973-977      |                 Available online, December 31, 2018

Evaluation of haematological parameters as a risk factor for head and neck cancer

Papa Kusuma B1, Lakshmi Kalpana V2, Uma Bharathi H1, Anuradha A3 and Aaren V4


1Research Scholar, Department of Human Genetics, Andhra University, Visakhapatnam, Andhra Pradesh, India.

2Head of the Department, Department of Human Genetics, Andhra University, Visakhapatnam, Andhra Pradesh, India.

3Post doc fellow, Department of Human Genetics, Andhra University, Visakhapatnam, Andhra Pradesh, India.

4Clinical Research Manager, Strand Life sciences, Bangalore, Karnataka, India.



Received: 01.11.2018        |       Accepted: 29.11.2018        |     Published: 31.12.2018

Head and Neck Squamous Cell Carcinoma (HNSCC) is a major health problem, accounting for 30-40% cancers at all sites. As various substances alter quantitatively in the serum during tumour development, we intended to explore the changes in the haematological profile in cases of HNSCC. Moreover, such studies on HNSCC patients are scanty in the North Coastal Andhra Pradesh, India. The present study is all about assessing the variations of haematological parameters in HNSCC patients. Biochemical characterization was done using standard protocols. Results were statistical analysed using Graph pad prism 7 software. Our study confirmed among different haematological parameters that there was no  statistical significance found  for serum creatinine, total bilirubin, haemoglobin, neutrophils, lymphocytes, haematocrit (PCV), Mean Cell Volume (MCV), Mean Cell Haemoglobin (MCH) and Mean Cell Haemoglobin Concentration (MCHC) and the statistical significance observed only for RBC count.


Keywords: Head and Neck Squamous Cell Carcinoma, Haematological parameters, Larynx , Pharynx




Editor: Dr.Arvind Chavhan


Cite this article as:

Papa Kusuma B, Lakshmi Kalpana V, Uma Bharathi H, Anuradha A and  Aaren V (2018) Evaluation of haematological parameters as a risk factor for head and neck cancer, Int. J. of. Life Sciences, Volume 6(4): 973-977.


Conflicts of interest: The authors stated that no conflicts of interest.



Copyright: © 2018 | Author(s), This is an open access article under the terms of the Creative Commons Attribution-Non-Commercial - No Derives License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.


Addala L et al., (2012) Risk factor profiles of head and neck cancer patients of Andhra Pradesh, India, Indian Journal of Cancer, Volume. 49, Issue (2), PP: 215-219.

Argiris A, Brockstein BE, Haraf DJ et al., (2004) Competing causes of death and second primary tumors in patients with locoregionally advanced head and neck cancer treated with chemoradiotherapy, Clinical Cancer Research, Vol. 10, Issue (6), PP: 1956–1962.

Argiris, Karamouzis MV, Raben D and Ferris RL (2008) Head and neck cancer, The Lancet, Vol. 371, Issue (9625), PP:.1695–1709.

Beahrs O, Henson DE, Hutter RV and Kennedy BJ, editors (1992) Manual for staging of cancer”, 4th edition (American Joint Committee on Cancer) Philadelphia: J.B. Lippincott Company.

Denaro N et al., (2011) The Role of p53 and MDM2 in Head and Neck Cancer”, ISRN Otolaryngology.

Dikshit RP and Kanhere S (2000) Tobacco habits and risk of lung, oropharyngeal and oral cavity cancer: A population-based case-control study in Bhopal, India, Int J Epidemiol,, Vol.29, PP:609-14.

Iype EM, et al., (2001). “Squamous cell carcinoma of the tongue among young Indian adults. Neoplasia”Vol.3, PP:273-7.

Khandekar SP, Bagdey PS and Tiwari RR (2006). “Oral Cancer and Some Epidemiological Factors: A Hospital Based Study”, Indian J Community Med, Vol.31, PP:157-159.

Sherin N, et al., (2008). “Changing trends in oral cancer”, Indian J Cancer, Vol.45, PP:93-96.

Vissink. A, J. Jansma, F. K. L. Spijkervet, F. R. Burlage, and R. P. Coppes, “Oral sequelae of head and neck radiotherapy”, Critical Reviews in Oral Biology and Medicine, Vol. 14, Issue(3), PP: 199–212, 2003.

Wei Gao, John Zeng Hong Li, Jimmy YuWaiChan,WaiKuenHo, and Thian-Sze Wong, mTOR Pathway and mTOR Inhibitors in Head and Neck Cancer”, ISRN Otolaryngology, Volume 2012.  







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