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Life Sciences

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ISSN  2320-964X (Online) 
ISSN 2320-7817  (Print)
Type - Quarterly 

 

Original Research

   Year 2013 |  Vol. 1 | Issue 2 | Page Nos. 133-142

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The effects of chloroform extract of Psoralea corylifolia seed on reproductive abilities of male albino rats

 

DABHADKAR DK1, ZADE VS*1, DHORE MM2 AND PATIL SS3

 

1Department of Zoology, Government Vidarbha Institute of Science and Humanities, Amravati- 444604, Maharashtra, India.

2Department of Botany, B.B. Arts, N. B. Commerce and B. P. Science College, Digras- 445 203, Maharashtra, India

3Director, Student Welfare, Sant Gadge Baba Amravati University, Amravati- 444 602, Maharashtra, India.

*Corresponding author: Dr. Varsha S. Zade, Associate Professor, Department of Zoology, Government Vidarbha Institute of science and Humanities, Amravati. India.

 

  © 2013|IJLSCI. All right reserved 

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The aim of the study is to evaluate the effect of the chloroform extract of Psoralea corylifolia on reproductive abilities of male albino rats. The chloroform extracts of P. corylifolia seeds at doses of 100, 200 and 400 mg/kg were administrated for 21 days. The sperm count of experimental animal was determined. The effect of the extract on body weight, reproductive and vital organ weight were determined. The effective chloroform extract were further studied for its effect on hormonal assay and compared with the standard reference drug sildenafil citrate. Similarly adverse effects and acute toxicity of the extract were also evaluated. Oral administration of chloroform at doses of 100, 200 and 400 mg/kg were significantly increased the sperm count in experimental animal. There was significant increase in level of testosterone in the serum with increase in the LH and FSH concentration. The extract was also observed to be devoid of any adverse effects and acute toxicity. The results of the present study demonstrate that chloroform extract of P. corylifolia seed enhance sexual behavior in male rats. It also thus provides a rationale for the traditional use of P. corylifolia as acclaimed aphrodisiac and for the management of male sexual disorders.

 

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