Image description

Life Sciences

Image description

_____________________________________________

RESEARCH ARTICLE

Volume 3 | Issue 1 |  March 2015 


Page Nos. 85-90

Date of Online 30 March, 2015

 

PDF access policy
Journal allows immediate open access to content in PDF     ___________________________________________________

Bookmark and Share

NEWS AND ANNOUNCEMENTS

-----------------------------------------------------------

CALL FOR PAPERS

IJLSCI Vol. 5 (3) September 2017

Last Date for article submission

July 25, 2017

Email your Valuable Research to

 editorijlsci@gmail.com OR editor@ijlsci.in

  

Synergistic response of Azadirachta spp. and Syzygium spp. on some fungi due to immunomodulators

  

Dassharma Kakoli 1, Bagkar Pratik2*  and  Ravnang Pratik3

 

1Department of Botany, Bhavan’s College, Andheri, 400058

2Department of Biotechnology, Ruia College, Matunga, 400019.

3Department of Botany, Savitribai Phule Pune University, Ganeshkhind, Pune -411007.

*Corresponding author email: bagkarpratik@yahoo.com

---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

ABSTRACT

............................................................................................................................................................................................................................................

Medicinal herbs act as immunomodulators supporting the body’s immunity system to deal with allergens. Since  Neem and Clove  are great source  of  traditional medicines, they were taken up as tool for our study to evaluate their lethal effects on three fungi- Aspergillus, Candida  and Penicillium spps.  using ethanolic and acetone solvent extracts through Disc Diffusion method. It was clearly observed that  Neem had better efficacy as compared to Clove since it showed appreciably higher potency in both the extracts. However the results of the comparative potential of  Neem in three fungi was found to be most in Penicillium followed by Aspergillus and least in Candida.  Another method was carried out using Well Diffusion method where three different ratio concentrations of  Clove  : Neem (1:2, 1:1, 2:1) were taken using ethanolic and acetone extracts separately and tried on three organisms at individual level. The result noted showed best antifungal response in 1: 1 followed by  1 : 2 and minimum effect by 2 : 1 which hinted the possibility of the enhanced effect of  Clove when paired with Neem. The above experiments proved Neem to be a better fungicide and also yielded enhanced effect when in mixture with Clove.

 

The Spectrophotometric readings for the presence of Flavonoids, phenols, and sterols provided us with the information which showed the concentration of phenols to be more than the others which lead us to believe that in all probability phenols is the active principle behind the better efficiency of  Azadirachta as compared to Clove as a fungicide and thus can be pursued as a source of alternative medicine.

 

Keywords: Neem, Clove, fungicide, well diffusion method, disc diffusion method, Synergistic.

 © 2015 |IJLSCI

............................................................................................................................................................................................................................................

ARTICLE INFO

Received: 01 January, 2015   |    Revised : 11 February, 2015

Accepted: 24 February, 2015  |   Published : 30 March, 2015

............................................................................................................................................................................................................................................

Editor: Dr. Arvind Chavhan 

............................................................................................................................................................................................................................................

Cite this article as:

Dassharma Kakoli, Bagkar Pratik  and  Ravnang Pratik (2015) Synergistic response of Azadirachta spp. and Syzygium spp. on some fungi due to Immunomodulators, Int. J. of Life Sciences, 3(1): 85-90.

............................................................................................................................................................................................................................................

Copyright: ©  2015 | Author(s), This is an open access article under the terms of the Creative Commons Attribution NonCommercial- No Derivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

............................................................................................................................................................................................................................................ 

GET ALERT FOR THIS JOURNAL

--------------------------------------------------------------------

Get the table of contents of every new issue published in IJLSCI.


OUR OTHER JOURNAL

-------------------------------------------------------------

ISSN:2322-0015

International Research Journal of Science & Engineering


Editor in Chief:

Dr. Arvind Chavhan

 

Type: Bimonthly,

INTERNATIONAL JOURNAL OF

LIFE SCIENCES

Print ISSN : 2320-7817 

Online ISSN:2320-964X

UGC Approved Journal No. 48951


EDITORIAL OFFICE

46, Guruwandan, Jawahar Nagar, 

VMV Road, Amravati- 444604

Maharashtra, India.

Tel  + 91- 9970559438

Email: editor@ijlsci.in