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Life Sciences

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RESEARCH ARTICLE

Volume 3 | Issue 2 |  June 2015 


Page Nos. 176-180

Date of Online 30 June, 2015

 

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IJLSCI Vol. 5 (4) December 2017

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NF1 gene Analysis: New paradigm by computational approach

 

 

Jadhav VA1,2 and  Laeequr Raheman3        

 

 

1Department of Biophysics, D.B. College, Bhokar, Nanded, MS, India -431801

2School of Life Science, SRTM University, Nanded, 431606, MS, India.

3MGM’S college of CS & IT, Nanded, 431601, MS, India

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ABSTRACT

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Now a day, we are having good stimulation and regulation due to small piece of evolutionarily developed nucleotides working dynamically called gene (eg.NF1). The malfunctioning of NF1is autosomal dominant condition, contributes a set distinct genetic disorder that that cause tumors to grow along various types of nerve. In addition, it can affect the development of non-nervous tissue such as bone and skin. The NF1 gene, encodes for protein called neurofibromine, belongs to family of protein that serve as negative regulators ras oncogene. The GRD region encoded by exons 20-27a, is the function ascribed region. We are aiming to identify and analyze with structure prediction.

 

Keywords: structure prediction, autosomal dominant, NF1, GRD.

 © 2015 |IJLSCI

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ARTICLE INFO

Received: 22.04.2015  |   Revised : 21.05.2015    |    Revised received: 13.06.2015

Accepted: 16.06.2015  |    Published : 30.06.2015

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Editor: Dr. Arvind Chavhan 

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Cite this article as:

Jadhav VA and  Laeequr Raheman (2015) NF1 gene Analysis: New paradigm by computational approach. Int. J. of Life Sciences, 3(2): 176-178.

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Copyright: ©  2015 | Author(s), This is an open access article under the terms of the Creative Commons Attribution NonCommercial- No Derivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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