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Life Sciences

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RESEARCH ARTICLE

Volume 3 | Issue 2 |  june 2015 


Page Nos. 141-146

Date of Online 30 June, 2015

 

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Impact of Heavy metal, Arsenic trioxide on Biochemical profile of 

teleost, Clarias batrachus (Linn.)

 

Pundir  Garima1* and  Pundir Himanshu2        

 

1Department of Zoology , R. G. (P.G) College, Meerut UP, India

2Department of Computer Science and Technology, Radha Govind Engineering College Meerut UP, India, 

Address for correspondence Email: gaarimaa112@yahoo.co.in

 

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ABSTRACT

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The present investigation aims at evaluating  the toxic effect of heavy metal, Arsenic trioxide on biochemical  profile of Clarias batrachus after 30, 45 and 60 days of post treatment with experimental chemical , arsenic trioxide.  Lc 50 value calculated  for sublethal study  of arsenic trioxide was 8.7 mg/l. Following biochemical parameters were analysed: Serum Protein, Serum Cholesterol. Serum Glucose, Acid phosphatase and Alkaline phosphatase. Decrease in serum protein observed in present study was   due to liver cirrhosis or nephrosis. Increase in cholesterol indicated environmental stress in Clarias batrachus .The significant reduction in plasma glucose levels during acute treatment indicates hypoxic condition. Increased stimulation of alkaline phosphatase corresponds to pathological processes as liver impairment, kidney dysfunction and bone disease.


Keywords: Arsenic trioxide, Clarias batrachus, Lethal concentration , Acid phosphatase, Alkaline phosphatase.

 © 2015 |IJLSCI

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ARTICLE INFO

Received: 03.03.2015    |      Revised : 13.04.2015

Accepted: 03.06.2015   |      Published : 30.06.2015

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Editor: Dr. Arvind Chavhan 

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Cite this article as:

Pundir  Garima and Pundir Himanshu   (2015) Impact of Heavy metal, Arsenic trioxide on Biochemical profile of teleost, Clarias batrachus (Linn.). Int. J. of Life Sciences, 3(2): 141-146.

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Copyright: ©  2015 | Author(s), This is an open access article under the terms of the Creative Commons Attribution NonCommercial- No Derivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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